Gender Differences in Non-Obstructive Coronary Artery Disease

Author(s): Maria Bergami, Marialuisa Scarpone, Edina Cenko, Elisa Varotti, Peter L. Amaduzzi, Olivia Manfrini*

Journal Name: Current Pharmaceutical Design

Volume 27 , Issue 29 , 2021

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Subjects affected by ischemic heart disease with non-obstructive coronary arteries constitute a population that has received increasing attention over the past two decades. Since the first studies with coronary angiography, female patients have been reported to have non-obstructive coronary artery disease more frequently than their male counterparts, both in stable and acute clinical settings. Although traditionally considered a relatively infrequent and low-risk form of myocardial ischemia, its impact on clinical practice is undeniable, especially when it comes to infarction, where the prognosis is not as benign as previously assumed. Unfortunately, despite increasing awareness, there are still several questions left unanswered regarding diagnosis, risk stratification and treatment. The purpose of this review is to provide state of the art update on the current evidence available on gender differences in clinical characteristics, management and prognosis of ischemic heart disease with non-obstructive coronary arteries, both in the acute and stable clinical settings.

Keywords: Non-obstructive CAD, MINOCA, women, female sex, sex differences, gender differences, prognosis.

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Article Details

Year: 2021
Published on: 12 October, 2020
Page: [3198 - 3209]
Pages: 12
DOI: 10.2174/1381612826666201012163845
Price: $65

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