Primary Breast Angiosarcoma: Utilisation of Pre-Surgical Magnetic Resonance Imaging (MRI) for Accurate Tumour Characterization and Planning – A Case Report and Literature Review

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Author(s): Nazimah Ab Mumin, Kartini Rahmat*, Marlina Tanty Ramli Hamid, Ng Wei Lin, Chan Wai Yee, Cheah Xin Ying, See Mee Hoong, Yip Cheng Har

Journal Name: Current Medical Imaging
Formerly: Current Medical Imaging Reviews

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Background: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings. Case report: A 30-year-old lady presented with left breast pain and lumpiness over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy.

Discussion: Literature review on imaging findings of breast angiosarcoma especially on MRI is discussed. MRI features are heterogenous low signal intensity on T1 and high signal intensity in T2. Dynamic contrast enhancement (DCE) features are either early enhancement with or without washout in the delayed phase. Some reported central areas of nonenhancement.

Conclusion: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay.

Keywords: Breast angiosarcoma, magnetic resonance imaging (MRI), ultrasound elastography, digital breast tomosynthesis(DBT), primary breast angiosarcoma, breast cancer

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(E-pub Ahead of Print)
DOI: 10.2174/1573405616666201007161119
Price: $95

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