Currently, there is a growing interest in the development of suitable methods for the
preparation of eco-friendly and biocompatible materials in order to increase environmental protection
and reduce human health risk. Therefore, this mini-review summarizes several studies involving
lactides and lactones as monomers for the synthesis of biodegradable and biocompatible polymers
via metal-catalyzed Ring-Opening Polymerization (ROP). Hence, synthetic approaches involving
mono, bi and trinuclear metallic catalysts, with different catalytic activity, were reviewed.
Complexes mostly based on metals such as Na, Mg, Al, Ti, Zn are considered. Generally, from
ROP reactions, it has been found that conversion, stereoselectivity, number-average molar mass
(Mn) and dispersity of the molar mass (Ð) of polymers are influenced by the type of monomer, the
characteristics of the catalyst, the nature of the solvent, temperature and reaction time. Additionally,
the polymer properties can also be controlled by varying the molar ratios between the monomer
and the initiating system. Thus, this review may be found helpful for the scientific community and
students involved in research in different areas of chemistry such as organic chemistry, inorganic
chemistry, polymers chemistry, and materials science. The survey covers selected data published
between 2017 and 2020; however, previous relevant reports were also studied.