Skin cancer remains a major cause of mortality worldwide. It can be divided into melanoma
and non-melanoma cancer, which comprise mainly squamous cell carcinoma and basal cell
carcinoma. Although conventional therapies have ameliorated the management of skin cancer, the
search for chemopreventive compounds is still the most effective and safer strategy to treat cancer.
Nowadays, chemoprevention is recognized as a novel approach to prevent or inhibit carcinogenesis
steps with the use of natural products. Crude extracts of plants and isolated phytocompounds are
considered chemopreventive agents since they harbor anti-inflammatory, antioxidant and anti-oncogenic
properties against many types of diseases and cancers. In this review, we will discuss the therapeutic
effect and preventive potential of selected medicinal plants used as crude extracts or as phytocompounds
against melanoma and non-melanoma cutaneous cancers.
Keywords: Skin cancer, phytocompounds, natural products, chemoprevention, melanoma, carcinoma.
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