β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of
medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral, antibacterial,
antifungal, antileishmanial, antimalarial, neuropharmacological, anti-inflammatory and antithrombotic
among others. β-Carbolines exhibit their pharmacological activity via diverse mechanisms.
This review provides a recent update (2015-2020) on the anti-infective potential of natural and synthetic
β-carboline analogs focusing on its antibacterial, antifungal, antiviral, antimalarial, antileishmanial
and antitrypanosomal properties. In cases where enough details are available, a note on its mechanism
of action is also added.