An Updated Review of Secondary Metabolites from Marine Fungi

Author(s): Syed Shabana, K. Rajya Lakshmi, A. Krishna Satya*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 21 , Issue 5 , 2021

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Graphical Abstract:


Marine fungi are valuable and richest sources of novel natural products for medicinal and pharmaceutical industries. Nutrient depletion, competition or any other type of metabolic stress which limits marine fungal growth promotes the formation and secretion of secondary metabolites. Generally secondary metabolites can be produced by many different metabolic pathways and include antibiotics, cytotoxic and cyto-stimulatory compounds. Marine fungi produce many different types of secondary metabolites that are of commercial importance. This review paper deals with around 187 novel compounds and 212 other known compounds with anticancer and antibacterial activities with a special focus on the period from 2011-2019. Furthermore, this review highlights the sources of organisms, chemical classes and biological activities (anticancer and antibacterial) of metabolites, that were isolated and structurally elucidated from marine fungi to throw a helping hand for novel drug development.

Keywords: Marine fungi, secondary metabolites, anticancer, antibacterial, novel drugs, natural product

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Article Details

Year: 2021
Published on: 05 March, 2021
Page: [602 - 642]
Pages: 41
DOI: 10.2174/1389557520666200925142514
Price: $65

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