Aim: The present work provides a fast, simple, accurate, and inexpensive analytical method for the
determination of Linagliptin (anti-diabetic drug).
Methods: The analysis was performed using a square wave adsorptive anodic stripping voltammetric technique
(SWAASV) and glassy carbon electrode (GCE) as a working electrode. The experimental and instrumental parameters
were studied and discussed to ensure the validity of the method.
Results: The method has a very good linearity (R2 = 0.9984), wide concentration range (0.189 - 2.268 μg mL-1),
low detection limit of 0.052 μg mL-1 and low quantitation limit of 0.172 μg mL-1.
Conclusion: Linagliptin was identified successfully using the proposed method in pharmaceutical formulations,
spiked human urine and plasma with 99.67, 91.96, and 92.78% recovery, respectively, and the results obtained
were compared with other reported methods.