Hantaviruses are rodent viruses that have been identified as etiologic agents of 2 diseases of humans: haemorrhagic fever with renal syndrome (HFRS) and nephropathia epidemica (NE) in the Old World and Hantavirus pulmonary
syndrome (HPS) in the New World. Orthohantavirus is a genus of single-stranded, enveloped, negative-sense RNA viruses
in the family Hantaviridae of the order Bunyavirales.The important reservoir of Hantaviruses are rodents.Each virus serotype has its unique rodent host species and transmitted to human beings with the aid of aerosolized virus which is shed in
urine, faeces and saliva and hardly by a bite of contaminated host. Andes virus, the only Hantavirus identified to be transmitted from human-to-human Major signs and symptoms consisting of fever, headache, muscle aches, lungs fill with fluid
etc. At early 1993 this viral syndrome showed in the Four Corners location in south western United States. Only accepted therapeutics for this virus is Ribavirin. Recently serological examinations to identify Hantavirus antibodies become most popular for investigation among humans and rodent reservoirs.
Keywords: Hantavirus, history, Pathogenesis, outbreak, Sigh-symptoms, transmission, treatment.
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