Abstract
COVID-19 is an emerging disease that is a major threat to the global community. The main challenge in this disease is the lack of proper or proven medication. The drugs used to treat this disease are only for symptomatic treatment. Studies of other coronaviruses, such as SARS and MERS, suggest that quercetin has sufficient potential to treat COVID-19. Previous studies have shown that quercetin reduces the entry of the virus into the cell by blocking the ACE2 receptor, as well as reducing the level of interleukin-6 in SARS and MERS patients. Therefore, the aim of this review was to scrutinize the potential of quercetin as a drug in the treatment of COVID-19 from a molecular perspective.
Keywords: Quercetin, therapeutic, COVID-19, ACE2, SARS, MERS.
Current Molecular Medicine
Title:Quercetin and its Relative Therapeutic Potential Against COVID-19: A Retrospective Review and Prospective Overview
Volume: 21 Issue: 5
Author(s): Saiyad Bastaminejad and Salar Bakhtiyari*
Affiliation:
- Department of Clinical Biochemistry, Faculty of Medicine, Ilam University of Medical Sciences, Ilam,Iran
Keywords: Quercetin, therapeutic, COVID-19, ACE2, SARS, MERS.
Abstract: COVID-19 is an emerging disease that is a major threat to the global community. The main challenge in this disease is the lack of proper or proven medication. The drugs used to treat this disease are only for symptomatic treatment. Studies of other coronaviruses, such as SARS and MERS, suggest that quercetin has sufficient potential to treat COVID-19. Previous studies have shown that quercetin reduces the entry of the virus into the cell by blocking the ACE2 receptor, as well as reducing the level of interleukin-6 in SARS and MERS patients. Therefore, the aim of this review was to scrutinize the potential of quercetin as a drug in the treatment of COVID-19 from a molecular perspective.
Export Options
About this article
Cite this article as:
Bastaminejad Saiyad and Bakhtiyari Salar *, Quercetin and its Relative Therapeutic Potential Against COVID-19: A Retrospective Review and Prospective Overview, Current Molecular Medicine 2021; 21 (5) . https://dx.doi.org/10.2174/1566524020999200918150630
DOI https://dx.doi.org/10.2174/1566524020999200918150630 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Scenario of the Treatment of Arthritis with Natural Products
Recent Patents on Inflammation & Allergy Drug Discovery The Spectrum of Biochemical Alterations with Molecular and Serological Biomarkers in the Diagnosis of COVID-19: Searching for Novel One to Identify Disease Earlier with Better Prognosis and Drug Discovery
Recent Advances in Anti-Infective Drug Discovery An Overview on Chemotherapy-induced Cognitive Impairment and Potential Role of Antidepressants
Current Neuropharmacology 1, 25(OH)<sub>2</sub>D<sub>3</sub> Inhibits Hepatocellular Carcinoma Development Through Reducing Secretion of Inflammatory Cytokines from Immunocytes
Current Medicinal Chemistry New Bis-Pyrazolones as Potential Leads for ROS Inhibition; Environment Friendly Green Synthesis, Structural Characterization, and In Vitro Studies
Medicinal Chemistry Effect of Glatiramer Acetate on Peripheral Blood Brain-Derived Neurotrophic Factor and Phosphorylated TrkB Levels in Relapsing- Remitting Multiple Sclerosis
CNS & Neurological Disorders - Drug Targets Mechanistic Insights into Aspartame-induced Immune Dysregulation
Current Nutrition & Food Science Pharmacological, Immunological, and Gene Targeting of the Renin-Angiotensin System for Treatment of Cardiovascular Disease
Current Pharmaceutical Design Cytokines Induced During Influenza Virus Infection
Current Pharmaceutical Design The Neonatal Kidney: Implications for Drug Metabolism and Elimination
Current Drug Metabolism Nuclear Export as a Novel Therapeutic Target: The CRM1 Connection
Current Cancer Drug Targets Efficacy of Duloxetine in Patients with Chronic Pain Conditions
Current Drug Therapy Monoclonal Antibodies as a Tool for Structure-Function Studies of the MDR1-P-Glycoprotein
Current Protein & Peptide Science Evaluation of the Physicochemical and Biopharmaceutical Properties of Fluoro-Indomethacin
Current Drug Metabolism Protein Regulators of Eicosanoid Synthesis: Role in Inflammation
Current Protein & Peptide Science Role of Heart Rate Reduction in the Management of Myocarditis
Current Pharmaceutical Design Role of the Receptor Tyrosine Kinase Axl and its Targeting in Cancer Cells
Current Medicinal Chemistry A Retrospective Study of Drug Induced Cutaneous Adverse Reactions (CADR) in Patients Attending a Tertiary Care Hospital
Current Drug Safety Anti-Angiogenesis in the Treatment of Genito-Urinary Cancers: Last Updates
Current Angiogenesis (Discontinued) Role of MicroRNA in the Diagnosis and Therapy of Hepatocellular Carcinoma: A New Frontier
MicroRNA