Background: Phytoestrogens are non-endocrine, non-steroidal secondary derivatives of plants and
consumed through a plant-based diet also named as “dietary estrogens”. The major sources of phytoestrogens
are soy and soy-based foods, flaxseed, chickpeas, green beans, dairy products, etc. The dietary inclusion of phytoestrogen
based foods plays a crucial role in the maintenance of metabolic syndrome cluster, including obesity,
diabetes, blood pressure, cancer, inflammation, cardiovascular diseases, postmenopausal ailments and their
complications. In recent days, phytoestrogens are the preferred molecules for hormone replacement therapy. On
the other hand, they act as endocrine disruptors via estrogen receptor-mediated pathways. These effects are not
restricted to adult males or females and identified even in development.
Objective: Since phytoestrogenic occurrence is high at daily meals for most people worldwide, they focused to
study for its beneficiary effects towards developing pharmaceutical drugs for treating various metabolic disorders
by observing endocrine disruption.
Conclusion: The present review emphasizes the pros and cons of phytoestrogens on human health, which may
help to direct the pharmaceutical industry to produce various phytoestrongen based drugs against various