Molecular Hydrogen Application in Stroke: Bench to Bedside

Author(s): Lei Huang, Cameron Lenahan, Warren Boling, Jiping Tang, John H. Zhang*

Journal Name: Current Pharmaceutical Design

Volume 27 , Issue 5 , 2021


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Abstract:

Stroke is a major cause of mortality and morbidity worldwide. Effective treatments are limited. Molecular hydrogen is emerging as a novel medical gas with therapeutic potential for various neurological diseases, including stroke. We reviewed the experimental and clinical findings of the effects of molecular hydrogen therapy in stroke patients and models. The underlying neuroprotective mechanisms against stroke pathology were also discussed.

Keywords: Ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, hydrogen gas, hydrogen-rich saline, hydrogen-rich water, antioxidant, neuroprotection.

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Article Details

VOLUME: 27
ISSUE: 5
Year: 2021
Published on: 17 September, 2020
Page: [703 - 712]
Pages: 10
DOI: 10.2174/1381612826666200917152316
Price: $65

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