Probiotics Against Viruses; COVID-19 is a Paper Tiger: A Systematic Review

Author(s): Zamzam Paknahad, Amir R. Moravejolahkami*

Journal Name: Endocrine, Metabolic & Immune Disorders - Drug Targets
Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 21 , Issue 7 , 2021

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Graphical Abstract:


Background: Probiotics can improve immune function leading to the prevention and management of viral infections like SARS-CoV-2 infection (COVID-19 disease).

Methods: We searched PubMed, EMBASE, Google Scholar, Science Direct, Scopus, and Web of Science up to May 2020 to identify interventional & observational studies documenting the effects of probiotics on incidence, severity, duration, and other clinical manifestations of viral infections, especially SARS-CoV-2-induced.

Results: From a total of 91 records, 24 studies were obtained and classified into three domains based on the efficacy of probiotics on 1) shortening the period and severity of infections (n=9), 2) incidence (n=6), and 3) other clinical complications that may be followed by viral disorders (n=9). Identified probiotics have positive effects on the mentioned domains.

Conclusion: Based on the evidence, some probiotic strains may be useful in SARS-CoV-2 infection; randomized trials are needed to show the facts.

Keywords: Viral diseases, probiotics, COVID-19, SARS-CoV-2, microbiome, immunity.

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Article Details

Year: 2021
Published on: 17 September, 2020
Page: [1252 - 1260]
Pages: 9
DOI: 10.2174/1871530320666200917114033
Price: $65

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