Applications of the Dess-Martin Oxidation in Total Synthesis of Natural Products

Author(s): Majid M. Heravi*, Tayebe Momeni, Vahideh Zadsirjan*, Leila Mohammadi

Journal Name: Current Organic Synthesis

Volume 18 , Issue 2 , 2021

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Graphical Abstract:


Dess–Martin periodinane (DMP), a commercially available chemical, is frequently utilized as a mild oxidative agent for the selective oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones, respectively. DMP shows several merits over other common oxidative agents such as chromiumand DMSO-based oxidants; thus, it is habitually employed in the total synthesis of natural products. In this review, we try to underscore the applications of DMP as an effective oxidant in an appropriate step (steps) in the multi-step total synthesis of natural products.

Keywords: Dess-Martin periodinane, DMP, oxidation, total synthesis, natural products, oxidation, alcohols, aldehydes, ketones.

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Article Details

Year: 2021
Published on: 16 September, 2020
Page: [125 - 196]
Pages: 72
DOI: 10.2174/1570179417666200917102634
Price: $65

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