Dess–Martin periodinane (DMP), a commercially available chemical, is frequently utilized as a mild
oxidative agent for the selective oxidation of primary and secondary alcohols to their corresponding aldehydes
and ketones, respectively. DMP shows several merits over other common oxidative agents such as chromiumand
DMSO-based oxidants; thus, it is habitually employed in the total synthesis of natural products. In this review,
we try to underscore the applications of DMP as an effective oxidant in an appropriate step (steps) in the
multi-step total synthesis of natural products.
Keywords: Dess-Martin periodinane, DMP, oxidation, total synthesis, natural products, oxidation, alcohols, aldehydes, ketones.
Rights & PermissionsPrintExport