Background: Gestational diabetes mellitus is a common medical disorder of pregnancy
associated with adverse outcomes for the mother and infant. This disease may result in maternal and
fetal morbidity and mortality. Although therapies are available for the management of diabetes,
which includes anti-diabetic drugs and insulin injections, yet continuous use of synthetic drugs provides
lower healing with many side effects.
Objective: The continuous search for effective anti-diabetic drugs from a natural source is the main
reason behind exploring marine resources for therapeutic and nutritional compounds.
Methods: As major articles of interest in the field of marine flora for gestational diabetes have been
found, so this review has been proposed based on relevant information. A description of the studies
is included in the review.
Results: Marine bio-resources produce several novel scaffolds, which show their good efficacy and
bioavailability in the treatment of gestational diabetes. Thus, marine resources have attracted much
interest of the scientific community.
Conclusion: This mini-review article presents some potential scaffolds from different marine
sources such as algae, sponges together with their specific activity. Concerning the maternal risk
factor, additional study is required.