Buruli Ulcer: Mycobacterium Ulcerans is the Causative Agent
Pp. 103-107 (5)
Muhammad Imran Qadir,
Buruli ulcer also called Brainsdale ulcer is the chronic, debilitating
subcutaneous destructive infection of the skin, soft tissue, and adipose tissue.
Mycobacterium ulcerans is the causative agent of BU. The infection of BU is prevalent
in many areas of the world. However, wetlands and tropic to sub-tropic areas are more
prone. The disease can be diagnosed by expert physicians as it can be confused with
the other skin infection.IS2404 PCR is mostly used for the diagnosis of BU. Antibiotics
and surgery are frequently used for the treatment. Heat treatment has also been found
effective for BU. The condition could lead to disabilities if not treated on time such as
amputation of the vital organ i.e. eye or the limbs. The affected person may face the
problem of social stigma and economic challenges as a consequence of these
disabilities. No vaccines are available yet for BU. However, short-lived protection is
obtained using the BCG vaccine. The disease is not fatal, however.
Deformities, Mycobacterium ulcerans, Necrotizing Ulceration,