Current Scenario and Future Prospect in the Management of COVID-19

Author(s): Pobitra Borah, Pran Kishore Deb*, Satyendra Deka, Katharigatta N. Venugopala, Vinayak Singh, Raghu Prasad Mailavaram, Kiran Kalia, Rakesh Kumar Tekade*

Journal Name: Current Medicinal Chemistry

Volume 28 , Issue 2 , 2021


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Abstract:

The COVID-19 pandemic continues to wreak havoc worldwide due to the lack of risk assessment, rapid spreading ability, and propensity to precipitate severe disease in comorbid conditions. In an attempt to fulfill the demand for prophylactic and treatment measures to intercept the ongoing outbreak, the drug development process is facing several obstacles and renaissance in clinical trials, including vaccines, antivirals, immunomodulators, plasma therapy, and traditional medicines. This review outlines the overview of SARS-CoV-2 infection, significant recent findings, and ongoing clinical trials concerning current and future therapeutic interventions for the management of advancing pandemic of the century.

Keywords: COVID-19, SARS-CoV-2, Cytokine Storm, Remdesivir, TCM, Convalescent Plasma, Vaccines.

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Article Details

VOLUME: 28
ISSUE: 2
Year: 2021
Published on: 30 December, 2020
Page: [284 - 307]
Pages: 24
DOI: 10.2174/0929867327666200908113642
Price: $65

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