Properties of Perhalopyridines
Pp. 1-7 (7)
Reza Ranjbar-Karimi and Alireza Poorfreidoni
The introduction of halogen atoms on the pyridine ring causes significant
changes in its properties. Halogens reduced basicity of pyridine ring as well as dipole
moment. The presence of dense halogen atoms renders a higher density of
perhalopyridines than pyridine. Fluorine atoms cause a low-field shift of pyridine
carbons than chlorine and bromine atoms. Perhalopyridines are mainly involved in
nucleophilic substitution reactions due to the electron-withdrawing nature of halogens
while perfluoropyridines are more active than others.
13C-NMR spectrum, 19F-NMR spectrum, Activating Effect, Addition-
Elimination Mechanism, Basicity, Chemical Shifts, Density, Dipole Moment,
Intermolecular Forces, IR spectrum, Meisenheimer Intermediate, Nucleophilic
Substitution, Pentabromopyridine, Pentachloropyridine, Pentafluoropyridine,
Raman Analysis, Shielding Effect, Spectroscopy, Steric Factors, UV-Vis
Department of Chemistry, Faculty of Science Vali-e-Asr University of Rafsanjan Islamic Republic of Iran.