Melatonin Could Be Beneficial in SARS-CoV-2 Therapy

Author(s): Sanaz Baghban Rahimi, Ahmad Hosseinzadeh Adli*

Journal Name: The Natural Products Journal

Volume 11 , Issue 5 , 2021


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Abstract:

Novel coronavirus (SARS-CoV-2) can infect the respiratory tract and cause severe respiratory syndrome. The excessive inflammatory response is involved in the pathogenicity of the SARS-CoV-2. Symptoms of SARS-CoV-2 are generally associated with immunopathogenesis and may result in pulmonary tissue damage. Melatonin is a natural and multifunctional hormone that is involved in both physiological and pathological conditions in the body, such as immune modulation, anti-inflammation, and antioxidant. Melatonin is found in foods, animal and human milk and increases the expression of anti-inflammatory cytokines and, as an adjuvant treatment in SARS-- CoV-2 infection, it may have considerable therapeutic potential, because of its safety and immunomodulatory effects.

Keywords: Melatonin, SARS-CoV-2, treatment, anti-inflammatory, immunomodulator, natural.

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Article Details

VOLUME: 11
ISSUE: 5
Year: 2021
Page: [598 - 606]
Pages: 9
DOI: 10.2174/2210315510999200905130902
Price: $95

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PDF: 130