Background: COVID-19 is a new, health-threatening infectious disease in the world in 2020
and is caused by a novel coronavirus SARS-CoV-2. As of July 13, 2020, 4,881,579 active cases of
COVID-19 were diagnosed, and 571,080 deaths were reported globally. In India, 301,850 active cases
and 23,187 deaths were reported. To date, no effective treatment is available against the deadly virus
SARS-CoV-2. Drug manufacturers, institutional laboratories, and other organizations have started developing
vaccines to combat COVID-19 infection.
Methods: Science Direct, Elsevier, PubMed, Scopus, and Nature databases were referred to know the
current scenario of the disease. Moreover, recent data have been obtained from the World Health Organization,
Centre of Disease Control, case studies, newspapers, and Worldometer reports. Data of Vaccine
Centre at the London School of Hygiene & Tropical Medicine, Clinicaltrials.gov, and US National
Library of Medicine have also been accessed to obtain the latest information about ongoing clinical trials.
Results: The primary source of the SARS-CoV-2 outbreak is connected to the Hunan seafood and live
animal market in Wuhan city, Hubei Province, China. Like; SARS-CoV, and MERS-CoV, SARS-CoV-
2 is also a zoonotic virus affecting the lower respiratory tract in humans. The pathogenesis of COVID-
19 involves attachment of its Spike (S) protein to the angiotensin-converting enzyme 2 (ACE2) receptor
in the lower respiratory tract in humans. The most common symptoms of COVID-19 are fever, cough,
sore throat, fatigue, headache, myalgia, septic shock, and breathlessness. Few patients with COVID-19
infection experience diarrhea, vomiting, and abdominal pain. Currently, FDA approved drugs being used
to treat COVID-19.
Conclusion: This review article presents the importance of traditional Indian herbs recommended by
AYUSH as precautionary and curative measures of COVID-19 until vaccines and drugs are made available.
Moreover, this article discussed the origin, symptoms, mode of transmission, management, and
diagnostics techniques for the detection of the SARS-CoV-2 virus.