Background: Economic development and vast changes in food habits have accelerated
the consumption of junk foods, which are the leading causes of several disorders that turn the majority
of the people to use various herbal formulations or drugs for preventing various lifestyle diseases.
Nutraceuticals are the borderline apparatus between nutrients and drugs that provide supplementation
of the particular nutrient with a favorable health effect.
Objective: Various nutraceutical compounds like vitamins, spices, polyphenols, prebiotics, and probiotics
in the form of powders, tablets, and capsules are currently marketed globally. Among them,
previous literature have reported that polyphenols are the most promising compounds that have
been proven to treat various chronic diseases like cancer, hypertension, diabetes mellitus (DM), osteoporosis,
osteoarthritis, dyslipidemia, multiple sclerosis, congenital anomalies, Alzheimer’s disease,
etc. It is warranted to discuss the benefits of nanoformulations of nutraceuticals.
Methods: We have searched PubMed using the keywords nutraceuticals, nanoformulations, therapeutic
approaches, bionanotechnology, and therapeutics. The relevant papers and classical papers
in this field were selected to write this review.
Results and Discussion: The different classifications of nutraceuticals were described in this review.
The comparison between the different categories of nutraceuticals with their nanoformulated
forms was made, explaining the benefits of nanoformulations regarding stability, bioavailability,
enhanced anti-oxidant properties, etc. A glimpse of the drawbacks of nanoformulations was also included.
Conclusion: The current review highlights an overview of various nanoformulated nutraceuticals
and their approach towards the treatment of multiple diseases.