Background: Outbreak of Coronavirus Disease-2019 (COVID-19) has sent billions of people
into lockdown. It has a negative impact on daily life, physical and mental health. Never before was seen
such a type of pandemic sparked by a coronavirus. It increased anxiety in the community. Impacts of
this disruption affect every sector such as health, finance, education, transport, agriculture, and economical
growth of countries. Most of the countries experience insecurity in these sectors.
Objective: To reduce the spread of the novel Coronavirus-2019 and to bridge the knowledge gap of the
research community, frontline health workers as well as those persons who are working in this regard to
improve critical health challenges so that the community can plan effective prevention. In the present
mini-review, we summarized the origin, route of transmission, current therapies of treatment, preventions,
viability and real facts of fatal disease novel Coronavirus-2019 (2019-nCoV).
Result: Achieving division of a large population into small-small groups and take RT-PCR tests on a
very large scale. It will help to identify and isolate an accurate infected person. Isolation of infected
cases and quarantine reduce the transmissibility of COVID-19.
Conclusion: Knowledge about real-time evolution and transmission of the emerging pathogens helps to
prevent its infection at all stages. To improve understanding of the risk, mechanism, and treatment in
response to COVID-19 is required encouraging case studies, effective treatment therapies, drug discovery
and developments. Make awareness in society about sanitation and avoid close contact to escape
COVID-19 infection are the best ways of protection.