Essential Techniques for Medical and Life Scientists: A Guide to Contemporary Methods and Current Applications- Part II

Essential Techniques for Medical and Life Scientists: A Guide to Contemporary Methods and Current Applications- Part II

This handbook covers some primary instruments-based techniques used in modern biological science and medical research programs. Key features of the book include introductory notes for each topic, a ...
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Raman Spectroscopy and Its Biomedical Applications

Pp. 62-84 (23)

DOI: 10.2174/9789811464867120010006

Author(s): Charu Arora*, Pathik Maji, P. K. Bajpai

Abstract

Raman spectroscopy is a significant characterization technique using inelastic scattering of light associated with molecular vibration to gather information about chemical fingerprints of tissues, cells or biofluids. Lack of sample preparation including chemical specificity and the ability to use advanced techniques in the visible or near-infrared spectral range have led versatility in biological applications of Raman spectroscopy. By Raman spectroscopy, the changes caused by diseases in tissues and organs can be accurately investigated and it is fast, non-invasive, economic and highly specific in comparison to other diagnostic and imaging techniques. It can provide quantitative molecular information for an objective diagnosis. Raman spectroscopy can measure both chemical and morphological information in samples and provide objective diagnosis for independent tissue samples of new patients. Some specific techniques and applications presented in this chapter which will demonstrate the potential of Raman spectroscopy for medical diagnostics, as well as the versatile interest in healthcare service.

Keywords:

Biomedical applications, Instrumentation, Raman spectroscopy, Structure determination.