Background: Obesity has been a serious health issue over the last decades both in the affluent western world
and developing countries. Obesity is linked with major health complications such as diabetes, cardiac disorder, cancer,
hypertension, sleep apnoea, etc. Available treatments such as bariatric surgery and pharmacotherapy are often
accompanied by adverse side effects and poor patient compliance. Nanotechnology is a discipline that is concerned with
material characteristics at nanoscale, and offers novel techniques for disease detection, management, and prevention.
Objectives: Recent progress in the field of obesity research at its interface with nanotechnology is our focus.
Nanomedicine has greatly enhanced the health status of the people suffering from obesity as it provides non-obtrusive
techniques for the management and treatment of obesity.
Methods: Literature survey was performed using PubMed, Science Direct, and Web of Science search engines with- terms
nanotechnology, nanomedicine and obesity. The research was focused primarily on articles published between the years
2000 and 2019.
Results: We have described original and innovative approaches in developments of nano-technology based drug delivery
strategies. Nanotechnology has been widely proposed to combine herbal medicine for the treatment of obesity, because
nano-structured systems might be able to potentiate the action of plant extracts, reducing the required dose and side
effects, and improving activity. This will offer a wide era of treatment options which will directly improve the patient’s
Conclusion: This review surveys recent developments of nanotechnology‐based drug delivery strategies are highlighted,
and discussed for obesity treatment with an emphasis on the enhanced therapeutic efficiency and minimized side effects.
The insights for future development related to the management of obesity are also discussed.