Fluoro-edenite (FE) is an asbestos-like amphibole present in the bentonitic lavas extracted
from a stone quarry in Biancavilla, a village sited in the Etnean Volcanic Area (Italy).
Thoracic pathologies are the results of excessive inflammatory processes that are the early response
of the immune system to inhaled fibers. As demonstrated for asbestos, fibers may trigger immune
system cells in an acute and/or chronic manner. This review aims to clarify the pathways of
inflammation in workers exposed to FE fibers.
Based on the articles reviewed, it seems that a permanent stimulus created by repeatedly inhaling
the FE fibers and their persistence in the body can act as a trigger both in promoting inflammatory
processes and in the immunological induction of autoimmune disease.