Aim: Favism is characterized as acute anemia, due to Glucose-6-phosphate dehydrogenase
(G6PD) deficiency as a result of fava beans intake. It is associated with paleness, jaundice, and hemoglobinuria.
In this study, signs, symptoms and therapeutic findings of the patients with hemolysis due
to G6PD deficiency were investigated in Shahid Madani Hospital of Khorramabad, Lorestan.
Methods: This is a single-center cross-sectional descriptive study that was conducted on all children
with G6PD deficiency-induced hemolysis.
Results: 308 children (64.3% male and 35.7% female) were included in this study. The most common
complaint was jaundice (82.5%) and the most common cause of hemolysis was the intake of fava bean
(85.7%). 68% of the children were treated with hydration/fluid therapy. Blood transfusion was conducted
in 36.36% of the cases and the mean of blood administered was 18.9 cc/kg.
Conclusion: In this study, hydration therapy was performed in most of the children presenting favism.
Also, the incorrect calculation of the amount of blood needed for transfusion increased the frequency
of blood transfusions and prolonged hospitalization time.