Frontiers in Enzyme Inhibition

Frontiers in Enzyme Inhibition

Enzyme Inhibition - Environmental and Biomedical Applications

Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for ...
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Current Potentialities and Perspectives of Enzyme Inhibition Based Biosensor

Pp. 97-121 (25)

Senthil Nagappan, Rajvikram Madurai Elavarasan, Nilavunesan Dhandapani and Ekambaram Nakkeeran

Abstract

A biosensor is an electrical device encompassing biological components, with the intent to detect and measure the concentration of the analyte in a sample. The applications of the biosensor are numerous including, but not limited to food, healthcare and environmental sectors. In particular, biosensors based on enzymatic inhibition are highly sensitive in monitoring the inhibitory analytes affecting the catalytic activity of enzymes. A careful selection of transducer, a biosensor component for transforming the biochemical signal to an electrical signal along with the choice of enzymes is crucial in determining the commercial viability of enzymatic inhibitory biosensor. This chapter highlights the recent studies as well as products available in the market related to biosensors based on enzymatic inhibition. Besides, the economic analysis of existing and futuristic biosensors is also discussed.

Keywords:

Analyte, Analytes, Allergens, Biosensor, Biochemicals, Detection, Enzymes, Environmental, Enzyme inhibition, Enzyme inhibition, Food industry, Healthcare, Heavy metal, Inhibition-based biosensors, Nerve agents, Pharmaceuticals, Potentiometric, Pesticide, Screening, Toxins, Transducer.

Affiliation:

Department of Biotechnology, Sri Venkateswara College of Engineering (Autonomous), Sriperumbudur Tk - 602 117, Tamil Nadu, India