New techniques in bioinformatics and the study of the transcriptome at a wide-scale
have uncovered the fact that a large part of the genome is being translated than recently perceived
thoughts and research, bringing about the creation of a various quantity of RNA with proteincoding
and noncoding potential. A lot of RNA particles have been considered as noncoding due to
many reasons, according to developing proofs. Like many sORFs that encode many functional
micro peptides have neglected due to their tiny sizes.
Advanced studies reveal many major biological functions of these sORFs and their encoded micro
peptides in a different and wide range of species. All the achievement in the identification of these
sORFs and micro peptides is due to the progressive bioinformatics and high-throughput
sequencing methods. This field has pulled in more consideration due to the detection of a large
number of more sORFs and micro peptides. Nowadays, COVID-19 grabs all the attention of
science as it is a sudden outbreak. sORFs of COVID-19 should be revealed for new ways to
understand this virus. This review discusses ongoing progress in the systems for the identification
and distinguishing proof of sORFs and micro peptides.