Zinc oxide (ZnO) is a metal oxide well known for its photocatalytic property and is
widely used in cosmetics. Lately, it has gained more importance in its biomedical applications, especially
in cancer therapy. Scientific works have elucidated the efficiency of ZnO nanoparticles
(NPs) against different cancer cell lines. There are safety concerns related to the usage of ZnO NPs
as the zinc ion concentration may lead to changes in the human body. This review covers the significant
pharmaceutical and biological aspects of ZnO NPs. Besides, this review updates ZnO NPs
revolutionary use in photodynamic therapy (PDT), where it can work wonders and pave the way
for novel therapeutic approaches against cancer.
Keywords: Zinc oxide, nanoparticles, cytotoxicity, photodynamic therapy, surface modification, cancer cell lines.
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