Cosmeceuticals are cosmetic products containing biologically active ingredients with attractive
properties (e.g. anti-oxidant, anti-inflammatory, anti-aging, photoprotective activity, etc.).
The aim of these compounds is to offer pharmaceutically therapeutic benefits. The active ingredients
can be extracted and purified from natural sources, including plants and animals, or be obtained by
biotechnological methodologies (e.g. fermentation, enzymatic synthesis, etc.). Recent years have
been increased interest in the design and development of bioactive compounds with cosmeceutical
applications and low toxicity. The enzymatic synthesis of bioactive esters, based on esterification or
transesterification, has attracted much interest because of the interesting properties of the resulting
products and because, by replacing traditional chemical catalysts, this approach leads towards the development
of more sustainable processes that follow the principles of Green Chemistry. This review
gives an overview of the excellent suitability of lipases as biocatalysts for producing bioactive compounds
with attractive properties for the cosmetics industry.