Background: Tuberculosis (TB) mono-infection has radiological features and typical
clinical manifestations that are easily recognized by clinicians. These radiological features and clinical
manifestations are often found to show atypical features in subjects coinfected with Tuberculosis-
Human Immunodeficiency Virus (HIV), making TB diagnosis and early management challenging
Objective: The aim of this study was to determine the relationship between the clinical and radiological
presentation of pulmonary TB patients with HIV coinfection at the Central General Hospital
Methods: This research was an observational analytic study with a cross-sectional method. A total
of 54 TB-HIV coinfected patients were analyzed to their sociodemographic characteristics, clinical
manifestations and chest radiographic features.
Results: The majority of subjects were of productive age (26-61 years), male (64.8%) and belonged
to the heterosexual group (90.7%). Weight loss (75.9%), cough (64.8%) and oral candidiasis
(53.7%) are the most common clinical manifestations found in subjects, especially in subjects
with CD4+ >200 cells/mm3. Atypical radiological features such as infiltration/consolidation
(59.3%), fibrosis (16.7%) and hillar lymphadenopathy (14.8%) are the most commonly obtained radiological
features of the subjects. From the results of the bivariate analysis, it was found that radiological
features in the form of infiltration/consolidation were more commonly found in subjects
with CD4+ <200 cells/mm3 (OR=1.254; 95% CI 1.059-1.568).
Conclusion: Based on the research that has been done, it can be concluded that there are no typical
radiological features and clinical manifestations in patients with TB-HIV infection.