Eggshell membrane (ESM), a protein and collagen-rich membrane between the eggshell
and egg white, has usually been regarded as waste and overlooked. However, its potential is now
being highlighted in many industrial and technological applications. In the literature, natural
bioactive compounds (NBCs) have been used together with various proteins.
Preparation and characterization methods of the eggshell and eggshell membrane are summarized.
Various studies showed the utilization of eggshell membranes as an adsorbent, scaffold, wound
dressing, and vascular graft. Due to the chemical composition of the eggshell membrane, its
superior binding and adsorptive properties increase the stability of the bioactive compounds.
This review focuses on the potential utilization of eggshell membranes as functional food and