Ascorbic acid is the most well-known vitamin found in different types of food. It has
tremendous medical applications in several different fields such as in pharmaceuticals, cosmetics,
and in organic synthesis. Ascorbic acid can be used as a substrate or mediator in organic synthesis.
In this review, we report ascorbic acid-catalyzed reactions in organic synthesis. Several examples
are included in this review to demonstrate that ascorbic acid is a versatile catalyst for the synthesis
of diverse organic compounds. Reactions catalyzed by ascorbic acid are performed in organic or
aqueous media. The ready availability and easy handling features of ascorbic acid make these procedures
Keywords: Ascorbic acid, catalyst, organic synthesis, pharmaceuticals, medicine, green chemistry, acid-catalyzed.
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