Advances in Research on the Preparation and Biological Activity of Maslinic Acid

Author(s): Jianqiang Deng, Huiyun Wang, Xiaodong Mu, Xiuting He, Fenglan Zhao, Qingguo Meng*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 21 , Issue 1 , 2021

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Graphical Abstract:


Maslinic acid, a pentacyclic triterpene acid, is mainly isolated from olives. Maslinic acid and its derivatives exhibit a broad range of biological properties, such as anti-inflammatory, anticancer, anti-diabetic, antimicrobial, neuroprotective and hepatoprotective activities. In this minireview, the progress of research on maslinic acid with regard to its bioactivities, extraction, semisynthetic preparation and patents is reported. The relationships between the structure and the activity of maslinic acid and its derivatives are also discussed.

Keywords: Maslinic acid, pentacyclic triterpene, extraction, semisynthetic, biological activity, structure-activity relationships.

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Article Details

Year: 2021
Published on: 22 July, 2020
Page: [79 - 89]
Pages: 11
DOI: 10.2174/1389557520666200722134208
Price: $65

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