In the recent past, next-generation sequencing (NGS) approaches have heralded the omics
era. With NGS data burgeoning, there arose a need to disseminate the omic data better. Proteogenomics
has been vividly used for characterising the functions of candidate genes and is applied in ascertaining
various diseased phenotypes, including cancers. However, not much is known about the role and application
of proteogenomics, especially Prostate Cancer (PCa). In this review, we outline the need for proteogenomic
approaches, their applications and their role in PCa.
Keywords: Prostate Cancer, Next-Generation sequencing, Genomics, Proteomics, Proteogenomics, Transcriptomics, Phosphoproteomics.
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