Intermolecular Haloamination: Double Functionalization for Accesses to Vicinal Haloamines Involving Alkenes and Alkynes

Title:Intermolecular Haloamination: Double Functionalization for Accesses to Vicinal Haloamines Involving Alkenes and Alkynes

Volume: 18 Issue: 3

Author(s): Yi-Ning Wang*, Gang Qi and Guo-Xiang Sun

Affiliation:

• Department of Pharmaceutical Engineering, Faculty of Science and Technology, Yancheng Institute of Technology, Yancheng,China

Keywords: Addition, aminohalogenation, C-C unsaturated bonds, haloamination, intermolecular haloamination, vicinal haloamine.

Abstract: Haloamination (or called aminohalogenation) upon the C-C unsaturated bonds is an important amino functionalization, which can introduce the halogen atoms accompanying with the amino groups into the substrate backbones in a tandem manner. Over the past two decades, it has drawn increasing attention due to its versatile applications. In this review, we will mainly focus on the synthetic strategies anchoring the intermolecular haloamination reactions achieved in the past few years. Limited by the length of the context, the intramolecular haloamination and the applications of the vicinal haloamines will not be involved.

Cite this article as:

Wang Yi-Ning *, Qi Gang and Sun Guo-Xiang , Intermolecular Haloamination: Double Functionalization for Accesses to Vicinal Haloamines Involving Alkenes and Alkynes, Mini-Reviews in Organic Chemistry 2021; 18 (3) . https://dx.doi.org/10.2174/1570193X17999200719134419