Premature Closure of the Foramen Ovale and the Ductus Arteriosus
Pp. 52-76 (25)
Eliane Lucas, Carla Verona Barreto Farias and Nathalie Jeanne Magioli Bravo-Valenzuela
The foramen ovale and the ductus arteriosus are fetal circulation shunt sites,
and the appropriate flow profile in these shunts allows the maintenance of fetal
hemodynamic stability. The presence of restrictive or closed foramen ovale and/or
ductus arteriosus may lead to poor fetal outcomes, such as right ventricular failure,
neonatal pulmonary hypertension, or even death. Fetal echocardiography is the main
tool for the diagnosis and assessment of premature closure of the foramen ovale and/or
ductus arteriosus, and its intrauterine and/or postnatal management. In some cases, fetal
intervention or soon after birth may be required in the presence of fetal hemodynamic
Abnormal cardiac position, Ductus arteriosus, Echocardiography,
Foramen ovale, Premature constriction of fetal ductus arteriosus, Restrictive or
closed foramen ovale.
Discipline of Pediatrics (Pediatric Cardiology), Department of Medicine, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro-RJ, Brazil.