Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles

Author(s): Laksmikanta Adak*, Tubai Ghosh

Journal Name: Current Organic Chemistry

Volume 24 , Issue 22 , 2020


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Abstract:

Heterocyclic compounds are the largely diverse organic molecules and find prevalent applications in the fine chemical industry, medicinal chemistry and agricultural science. They are also among the most commonly bearing frameworks in numerous drugs and pharmaceutical substances. Therefore, the development of convenient, efficient and environmentally benign methods to produce various types of heterocyclic compounds is an attractive area of research. For the synthesis and functionalization of heterocycles, enormous achievements have been attributed over the past decades. Recently, ironcatalyzed reactions have accomplished a noteworthy development in the synthesis of heterocycles. This review highlights some remarkable achievements in the iron-catalyzed synthesis of heterocyclic compounds published in the last five years.

Keywords: Catalysis, iron, earth-abundant transition metal, synthetic methods, five-membered heterocycles, six-membered heterocycles.

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Article Details

VOLUME: 24
ISSUE: 22
Year: 2020
Published on: 18 December, 2020
Page: [2634 - 2664]
Pages: 31
DOI: 10.2174/1385272824999200714102103
Price: $58

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