Title:Review on Synthesis of Bio-active Coumarin-fused Heterocyclic Molecules
VOLUME: 24 ISSUE: 22
Author(s):Geetika Patel and Subhash Banerjee*
Affiliation:Department of Chemistry, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Koni, Chhattisgarh, Pin-495009, Department of Chemistry, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Koni, Chhattisgarh, Pin-495009
Keywords:Couramarin-fused heterocyclic compounds, pyran-fused coumarin, pyrazolyl-fused coumarin, chromeno-chromenes,
miscellaneous coumarin-fused molecules, synthetic strategies, applications.
Abstract:The literature survey reveals that the individual coumarin and heterocyclic
molecules have biological and pharmaceutical activities. Moreover, integrated coumarinfused
heterocyclic compounds have shown interesting biological and physiochemical
properties and thus, designing and development of coumarin-fused heterocyclic molecules
are of great interest in the field of synthetic organic chemistry. Several coumarin-fused
heterocyclic molecules have been synthesized by using different strategies such as multistep
method, one-pot multi-component protocol, coupling and condensation method. The
wide applications of integrated coumarin-fused heterocyclic molecules stimulated interest
among researchers to develop different methodologies for the synthesis of novel fused
molecules. As a consequence, several research articles, papers and review articles have been published in the
literature. In this review article, we have presented various methods for the synthesis of different class of
coumarin-fused heterocyclic molecules and their applications in chemical, optical, pharmaceutical and other
useful applications.