Background: Helicobacter pylori is a slow-growing micro-aerophilic gram-negative organism
found in the stomach and duodenum. It is also associated with a number of stomach-duodenal
Material and Methods: There are invasive and non-invasive methods to detect Helicobacter pylori
infections. In a 13-months period, 101 patients with clinical signs of infection confirmed by biopsy
and Rapid Urease test as well as a culture were included in this study.
Results: There were significant correlations between breath urease test, anti-Helicobacter pylori
serum IgG and IgA as well as fecal Helicobacter pylori Ag with the gold-standard method,
(P=0.001) Moreover, there was a significant correlation between Monocytosis (P= 0.05) and goldstandard
Conclusion: Based on studies conducted on patients with Helicobacter pylori infection, noninvasive
diagnostics methods can be useful in the diagnosis of Helicobacter infections rather than evaluating
anti-Helicobacter pylori serum IgM and also increased blood monocytes could be a reliable
confirmation for detection. Furthermore, Monocytosis must be considered as a Helicobacter pylori
infection at the first step in an area with a high infected percentage.