Title:Assortment of Human Amniotic Membrane and Curcumin: a Potential Therapeutic Strategy for Burn Wound Healing
VOLUME: 15
Author(s):Ayesha Siddika, Md. Arifuzzaman, Liakat Hossain, Md. Hasib Adnan, Farzana Diba, Md. Zahid Hasan, S.M. Asaduzzaman and Md Jamal Uddin*
Affiliation:Institute of Tissue Banking and Biomaterial Research, Atomic Energy Research Establishment (AERE), Savar, Dhaka1349, Institute of Tissue Banking and Biomaterial Research, Atomic Energy Research Establishment (AERE), Savar, Dhaka1349, Institute of Tissue Banking and Biomaterial Research, Atomic Energy Research Establishment (AERE), Savar, Dhaka1349, Institute of Tissue Banking and Biomaterial Research, Atomic Energy Research Establishment (AERE), Savar, Dhaka1349, Institute of Tissue Banking and Biomaterial Research, Atomic Energy Research Establishment (AERE), Savar, Dhaka1349, Institute of Tissue Banking and Biomaterial Research, Atomic Energy Research Establishment (AERE), Savar, Dhaka1349, Institute of Tissue Banking and Biomaterial Research, Atomic Energy Research Establishment (AERE), Savar, Dhaka1349, Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul 03760
Keywords:Amniotic membrane, burn healing therapy, burn wound healing, curcumin, combined effects, therapeutic effects.
Abstract:Burn wound associated injury management is one of the major unresolved clinical concerns. Most of the drugs
and dressing materials found in the market cause dose escalation and even exert side effects. Besides, a severe burn injury
is susceptible to microbial infection that leads to prolonged hospital stay which ultimately causes a financial crisis to the
victims. To get rid of this problem, researchers are being interested in developing such materials that are cost-effective,
easily available and accelerate faster healing. Human amniotic membrane (AM) and various herbal extracts like curcumin
are a potential source of burn wound healing. AM has various healing properties and is being used as a best burn wound
dressing material for centuries. Similarly, curcumin has been proven as faster dressing material for the treatment of burn
injury. Since both AM and curcumin are a potential source of burn and wound healing, if a gel/agent could be formulated
by mixing these two things, this combination may be a potential therapeutic strategy to treat burn wound healing.