Background: Diabetes is the leading cause of non-traumatic amputation of the lower limb. Several factors
associated with amputation are described in the literature, but they remain not well studied in our context.
Objectives: Our aim is to determine the prevalence and factors associated with amputation in patients hospitalized for
Methods: This is a prospective cross-sectional study performed over the period from December 1, 2017 to June 30, 2018.
The patients included were those hospitalized for trophic disorders of the foot in patients with type 2 diabetes. The studied
parameters were: epidemiological, diagnostic, therapeutic and evolutionary data. An univariate analysis and then a binary
logistic regression identified the factors associated with lower limb amputation.
Results: We included 53 patients. A lower limb amputation was performed in 8 patients (prevalence of 15.1%). Univariate
analysis found as factors associated with major amputation: advanced age (p = 0.031); male gender (p = 0.003); use of
traditional treatment (p = 0.036); non-compliance with the diabetic diet (p = 0.016); stage D of the University of Texas
(UT) Classification (p = 0.029); grade ≥ 2 of the UT Classification (p = 0.002). Logistic regression finds only the
following two variables as independent factor associated with amputation: male gender (p = 0.004, OR = 36.1 and CI =
3.2-402.9); stage D of the UT classification (p = 0.014, OR = 21.3 and CI = 1.8-244.2).
Conclusion: Controlling these factors would allow better management of diabetes to avoid complications.