Prevalence and Factors Associated with Lower Limb Amputation in Patients Hospitalized for Diabetic Foot: A Cross-sectional Study

(E-pub Ahead of Print)

Author(s): Abdourahmane Ndong*, Jacques Noel Tendeng, Mohamed Lamine Diao, Diatou Gueye Dia, Amadou Diop Dia, Arona Ba, Adja Coumba Diallo, Diago Anta Dia, Blaise Magloire Ngouamba, Philippe Manyacka Ma Nyemb, Ibrahima Konaté

Journal Name: Current Diabetes Reviews

Article ID: e070520183473
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Background: Diabetes is the leading cause of non-traumatic amputation of the lower limb. Several factors associated with amputation are described in the literature, but they remain not well studied in our context.

Objectives: Our aim is to determine the prevalence and factors associated with amputation in patients hospitalized for diabetic foot.

Methods: This is a prospective cross-sectional study performed over the period from December 1, 2017 to June 30, 2018. The patients included were those hospitalized for trophic disorders of the foot in patients with type 2 diabetes. The studied parameters were: epidemiological, diagnostic, therapeutic and evolutionary data. An univariate analysis and then a binary logistic regression identified the factors associated with lower limb amputation.

Results: We included 53 patients. A lower limb amputation was performed in 8 patients (prevalence of 15.1%). Univariate analysis found as factors associated with major amputation: advanced age (p = 0.031); male gender (p = 0.003); use of traditional treatment (p = 0.036); non-compliance with the diabetic diet (p = 0.016); stage D of the University of Texas (UT) Classification (p = 0.029); grade ≥ 2 of the UT Classification (p = 0.002). Logistic regression finds only the following two variables as independent factor associated with amputation: male gender (p = 0.004, OR = 36.1 and CI = 3.2-402.9); stage D of the UT classification (p = 0.014, OR = 21.3 and CI = 1.8-244.2).

Conclusion: Controlling these factors would allow better management of diabetes to avoid complications.

Keywords: Diabetes, amputation, foot, surgery, non-communicable disease, Senegal

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Article Details

Article ID: e070520183473
Published on: 05 July, 2020
(E-pub Ahead of Print)
DOI: 10.2174/1573399816666200705205224
Price: $95

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