A Retrospective Study on Gloriosa Superba and Its Main Active Constituents

(E-pub Ahead of Print)

Author(s): Aishwarya Shriwastava, Vijay Chopra, Manish Vyas*, Gopal L. Khatik, Pramod Yadav, Jeena Gupta, Amrit Pal Singh

Journal Name: The Natural Products Journal


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Abstract:

Background: Gloriosa superba L. (G. superba) is a perennial creeper and climbs up to 5-7 meters. It belongs to the Liliaceae family and is native to Africa and South-East Asia. It is also categorised as an endangered plant may be due to its extensive use.

Objective: The objective of the present review is to explore anticancer potential with other pharmacological activities of G. superba and its active constituents.

Results: G. superba reported to have many chemical constituents including colchicine, β-sitosterol, glumicolchicine, blumicolchicine, 2-OH-6-MeO-benzoic acid, glorisine, tannins, colchicoside, cornigerine, and many more. Most of them are effective against cancer, gout, arthritis, ulcers, bleeding piles, impotence, snakebites, skin diseases, and leprosy. G. superba reported to have pharmacological activities like anticancer, anti-inflammatory, antioxidant, abortifacient, anti-ulcerogenic, anti-helminthic and antimicrobial.

Conclusion: The present review summarizes the anticancer potential of G. superba and its constituents. However, detail study is required to establish it as an effective anticancer drug.

Keywords: Gloriosa superba L., Anticancer, Colchicine, anti-inflammatory, colchicoside, conigerine

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Article Details

(E-pub Ahead of Print)
DOI: 10.2174/2210315510999200704141949
Price: $95

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