Arylpyrazoles: Heterocyclic Scaffold of Immense Therapeutic Application

Author(s): Garima Tripathi, Anil Kumar Singh*, Abhijeet Kumar*

Journal Name: Current Organic Chemistry

Volume 24 , Issue 14 , 2020

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Graphical Abstract:


Among the major class of heterocycles, the N-heterocycles, such as pyrazoles, are scaffolds of vast medicinal values. Various drugs and other biologically active molecules are known to contain these N-heterocycles as core motifs. Specifically, arylpyrazoles have exhibited a diverse range of biological activities, including anti-inflammatory, anticancerous, antimicrobial and various others. For instance, arylpyrazoles are present as core moieties in various insecticides, fungicides and drugs such as Celebrex and Trocoxil. The present review will be highlighting the significant therapeutic importance of pyrazole derivatives developed in the last few years.

Keywords: Pyrazole, anti-inflammatory, anti-malarial, anti-cancerous, anti-viral, antifungal.

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Year: 2020
Published on: 12 October, 2020
Page: [1555 - 1581]
Pages: 27
DOI: 10.2174/1570179417999200628035645
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