Background: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized
by a local or systemic inflammatory response. At present, the increasing research results show that the
pathogenesis of the disease is complex, and the methods of clinical treatment also show diversity. This
review analyzes and summarizes the existing mechanism research and drug treatment methods in order
to provide a reference value for further drug research and development.
Method: We carried out a thorough literature search using databases. According to the main purpose of
the article, irrelevant articles were excluded after further examination and directly relevant articles were
included. Finally, the information related to the article was summarized.
Result: In this article, seventy-four articles are included. According to related articles, there are mainly
four kinds of drugs, namely antimalarial drugs, glucocorticoids, immunosuppressive agents and biological
agents. About fifty-five articles summarized the drugs for the treatment of systemic lupus erythematosus.
The rest of the articles were related to the research progress of the mechanism of systemic lupus
Conclusion: This article describes the pathogenesis of systemic lupus erythematosus, and summarizes
the traditional and new therapeutic drugs, which is not only beneficial to the treatment of lupus erythematosus
patients, but also plays a vital reference significance for the future development of new systemic
lupus erythematosus drugs.