Artificial receptor-like structures such as molecular imprinted polymers (MIPs) are
biomimetic molecules are used to replicate target specific antibody-antigen mechanism. In MIPs, selective
binding of template molecule can be significantly correlated with lock and key mechanism, which
play a major role in the drug delivery mechanism. The MIPs are biocompatible with high efficiency and
are considered in several drug delivery and biosensor applications besides continuous and controlled
drug release leading to better therapeutics. There is a need to explore the potential synthetic methods to
improve MIPs with respect to the imprinting capacity in cancer therapeutics. In this review, we focus on
MIPs as drug delivery mechanism in cancer and the challenges related to their synthesis and applications.
Keywords: Molecular imprinting polymers, Biomimetic, Artificial receptor, Drug delivery mechanism, Antibody-antigen, Selective
binding, Biocompatible, Cancer.
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