Background: Cistus munbyi Pomel is a well-known medicinal plant
in Western Algeria for its several applications in medicine and food. This endemic
species from North Africa is poorly studied among the genus of Cistus, which
gives the opportunity to carry out original pharmacological studies to value this
Objective: To investigate the antioxidant and the antimicrobial activities of Cistus
munbyi, an endemic medicinal plant from Algeria.
Methods: The antioxidant properties of C. munbyi crudes extracts were evaluated
using the DPPH radical-scavenging activity tests. While their antimicrobial activity
was studied by the agar diffusion method and MICs determination against
eighteen bacterial and fungal strains, some of which were clinical.
Results: The obtained results showed that aqueous and ethanol extracts possess a
strong scavenging activity against DPPH radicals with EC50 values estimated at
1.12 and 8.31 μg/mL, respectively. On the other hand, extracts from C. munbyi
revealed homogeneous and good antimicrobial activity, in which the inhibition
zone diameters observed were ranging from 08 to 19 mm, and the MICs values
were included from 0.312 to 5.000 mg/mL. The aqueous extract was less active
except against Proteus mirabilis and Staphylococcus aureus.
Conclusion: The findings of this study indicate that C. munbyipossesses a strong
antioxidant activity and an interesting antimicrobial potential, which allows justifying
its uses by the local population in several applications. Therefore, C. munbyi
could be a good source of natural antioxidants and antimicrobial agents.