Background: Cistus munbyi Pomel is a well-known medicinal plant in Western Algeria for its several applications in medicine and food. This endemic species to North Africa is poorly studied among the genus of Cistus, which
gives the opportunity to carry out original pharmacological studies to value this medicinal plant.
Objective: To investigate the antioxidant and the antimicrobial activities of Cistus munbyi, an endemic medicinal plant to
Methods: The antioxidant properties of C. munbyi crudes extracts were evaluated using the DPPH radical-scavenging activity tests. While their antimicrobial activity was studied by the agar diffusion method and MICs determination against
eighteen bacterial and fungal strains, some of which were clinical.
Results: The obtained results showed that aqueous and ethanol extracts possess a strong scavenging activity against
DPPH radicals with EC50 values estimated at 1.12 and 8.31 µg/mL, respectively. On the other hand, extracts from C.
munbyi revealed homogeneous and good antimicrobial activity, in which the inhibition zone diameters observed were
ranging from 08 to 19 mm, and the MICs values were included between 0.312 and 5.000 mg/mL. Aqueous extract was the
less active except against Proteus mirabilis and Staphylococcus aureus.
Conclusion: The findings of this study indicate that C. munbyi possess a strong antioxidant activity and an interesting antimicrobial potential, which allow justifying its uses by the local population in several applications. Therefore, C. munbyi
could be as a good source of natural antioxidants and antimicrobial agents.