Title:Supramolecular Catalysis: An Efficient and Sustainable Multicomponent Approach to the Synthesis of Novel Hexahydro-4H-indazol-4-one Derivatives
VOLUME: 9 ISSUE: 2
Author(s):Jyoti Tiwari, Swastika Singh, Deepali Jaiswal, Amit Kumar Sharma, Shailesh Singh, Jaya Singh and Jagdamba Singh*
Affiliation:Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, S SKhannaPG College, Allahabad-211003, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002, Department of Chemistry, LRPG College, Sahibabad, Ghaziabad-201005, Department of Chemistry, Environmentally Benign Synthesis Lab, University of Allahabad, Allahabad-211002
Keywords:β-Cyclodextrin, one-pot, green synthesis, phase transfer catalyst, hexahydro-4H-indazol-4-one, aqueous medium.
Abstract:We have developed an efficient, novel one-pot multicomponent protocol for the synthesis
of hexahydro-4H-indazol-4-onederivatives using β-cyclodextrin as a biomimetic catalyst in an aqueous
medium. To the best of our knowledge, the targeted molecules have not been reported in the literature
till now. The present method is very effective for our densely functionalized and diversified targeted
molecules and includes several advantages like environment benign, cost-effectiveness, short
reaction times, high yields and recyclability of the catalyst.
