Glioma is known as one of very important tumors that is associated with high
rate of mortality worldwide. The mean rate of survival of these patients has not changed
(approximately 14 months) even with improvements in comprehensive therapeutic
approaches, such as chemotherapy, radiation, and surgery. Therefore, it seems that
new therapeutic or developed platforms are needed. In this regard, more understanding
about genetic and epigenetic modifications in the glioma, could contribute to finding and
developing these platforms. Among epigenetic mechanisms, circular RNAs have crucial
roles in the glioma pathogenesis. Reported by several studies, some of the abilities of
circRNAs include the exhibition of tissue specificity in humans and regulation of genes.
Research has also confirmed the participation of circRNAs in different pathological or
biological procedures, including migration, invasion, and apoptosis of glioma. Herein, we
summarized circular RNAs involved in glioma.