Replacing harmful organic solvents that caused environmental pollution with an
alternative medium for the development of ideal synthetic strategies is one of the primary
focal points of green chemistry. Utilizing polyethylene glycol (PEG) as a nonvolatile solvent
and promotor for the evaluation of safe processes has made a considerable contribution to
the reduction of pollution problems. The current review summarizes the recent well-known
catalyst-free organic reaction performed in polyethylene glycol as a green and
biocompatible reaction medium.
Keywords: Polyethylene glycol, catalyst-free, organic compounds, green synthesis, reaction media, non-volatile solvent.
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